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(Each one contains as much nicotine as 590 cigarettes, according to one estimate.) Addison said that during her period of most intense use, her gums turned gray

But their powerful effects can be dangerous if misused

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They have published a number of high profile papers, including one on how gut bacteria predicts an individuals glucose response to bread ( Cell Metabolism 2017), another on personalized nutrition with CGM and microbiome data ( Cell 2015), and a third on how artificial sweeteners affect the microbiome and glucose responses ( Nature 2014)

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