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Next-Generation Dual and Triple Receptor Agonists: Formulation of two dual GLP-1/GIP (glucose-dependent insulinotropic polypeptide) agonists such as tirzepatide and the upcoming triple GLP-1/GIP/glucagon agonists are a paradigm shift in the management of metabolic diseases

For patients taking multiple medications, PlexusDx's Precision Peptide Genetic Test ($99 add-on after the first month) analyzes key genetic variants like GLP1R rs6923761 and MC4R rs17782313 that influence your individual response to GLP-1 therapy, helping fine-tune your medication selection and expected results

(D) A schematic of the gene that is expressed in the Glp-1r / mice

GLP-1s and dual GIP/GLP-1 agonists act on three key systems: blood sugar regulation, brain signals, and stomach fullness signals, says Dr

Note: whole-food supplements are not a substitute for a healthy dietthey are a supplement to an already good diet