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Gomisin A, another active lignan, increased the microsomal activity of cytochrome B5, cytochrome P450, nicotinamide adenine dinucleotide phosphate (NADPH) cytochrome C reductase, N-demethylase and 7-ethoxycoumarin O-deethylase while reducing the activity of 3,4-dibenzopyrene hydroxylase

One way that this could cause the symptoms seen in MCS is that oxidative stress can cause neurogenic inflammation due to the vulnerability of the central nervous system to free radicals.[ref] Combination of oxidative stress and odorant reactions

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