The Journal of biological chemistry 288 , 1987019881, doi: 10.1074/jbc.M112.448290 (2013)
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Dose Range: 50100 mg daily
If approved, widespread use will rapidly surface real-world safety signals
Severe constipation, ileus, and bowel obstruction that can turn surgical GLP 1 medicines slow gastric emptying, and they can slow gut transit more broadly