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Oral Wegovy: A Pill for Weight Management Wegovy is not just injectable
6-Gingerol enhanced autophagy-dependent ferroptosis of lung cancer cells by decreasing the expression of autophagy-related proteins ubiquitin-specific peptidase (USP14) and increasing iron concentrations and ROS levels, thereby presenting an anti-tumor effect in vivo and in vitro (Tsai et al., 2020)
demonstrated that high glucose significantly promotes TGF-1 secretion in HK-2 renal tubular cells, triggering ferroptosis via the TGF-1/Smad3 signaling pathway, while sleeve gastrectomy alleviates the symptoms and progression of diabetic kidney disease by downregulating this pathway [135]
Iron homeostasis and the inflammatory response
Clinical guidelines for prevention and treatment of type 2 diabetes mellitus in the elderly in China (2022 edition)
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