Additional information Prior Presentation: This manuscript is based on work that was presented at the American Diabetes Association83rd Annual Scientific Sessions, San Diego, CA, USA, 2326 June 2023: 769-P: Effect of food on the pharmacokinetics, safety and tolerability of orforglipron (LY3502970) an oral, non-peptide GLP-1 receptor agonist
KPV: inflammation control KPV is a three-amino-acid fragment of alpha-MSH, a natural anti-inflammatory hormone
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The study found that ME/CFS patients have significantly elevated IgA and IgM antibodies directed against the lipopolysaccharides (LPS) of enterobacteria, proving the presence of "leaky gut." Crucially, the researchers demonstrated that when these patients were treated with specific natural anti-inflammatory substancesprimarily L-Glutamine, combined with N-acetyl cysteine (NAC) and zinc, in conjunction with a leaky gut diet for 10-14 monthsthe leaky gut barrier was restored
