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There are two major types of free radical species: reactive oxygen species (ROS) and reactive nitrogen species (NOS)

10.1172/JCI73939 65 KostopoulouE.AnagnostisP.BosdouJ

Cell 185 , 42984316 (2022)

Previous studies have shown that ferroptosis in osteoblasts could be induced by a variety of pathological conditions, which is manifested by a decrease in the osteogenic differentiation of mesenchymal stem cells, as well as the decreased cell activity of mature osteoblasts and the damaged function of extracellular matrix mineralization [8, 9]

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