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A B12 shot is an intramuscular injection of vitamin B12, an essential nutrient involved in cellular energy production, nerve health, and DNA synthesis

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Thus, all patients were followed from study cohort entry until one of the study outcomes (described below), treatment discontinuation, initiation of a study drug in the comparator group, death from any cause (depending on the outcome), end of registration, or the end of the study period (29 March 2021), whichever came first