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For example: People put on GLP-1 drugs might differ in meaningful ways from those started on SGLT-2s or DPP-4s Severity of diabetes, weight, blood pressure patterns, sleep apnea, smoking history, and other factors can be hard to capture perfectly in claims Diagnostic coding can be imperfect Follow up time was up to 18 months, not years That said, the study is large, and it tries to do the comparison thoughtfully

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No entanto, importante notar que essas observaes provm exclusivamente de estudos animais e que os dados de segurana em humanos permanecem muito limitados