how does glp-1 work Glucagon-like peptide-1 How do GLP-1 Agonists Work?

Chadwick et al., 2000

MC1R activation in melanocytes triggers the switch from pheomelanin (light, yellow-red pigment) to eumelanin (dark, brown-black pigment) production, producing the tanning effect without requiring UV radiation

Bottom line, while these medications are amazing compared to prior classes of medications, they should be employed when lifestyle and diet regimens fail

Glutathione inhibits tyrosinase activity systemically and provides systemic antioxidant protection against UV-triggered melanin overproduction addressing pigmentation from inside the body

GHK-Cu is sensitive to pH, temperature, and oxidation