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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

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Neurosci Biobehav Rev 74:7697 Peterson R, Turnbull J (2012) Sonic hedgehog is cytoprotective against oxidative challenge in a cellular model of amyotrophic lateral sclerosis

Hepatotoxic drugs can cause injury to the hepatocytes directly in a predictable dose-dependent way or through idiosyncratic reactions

Kuehn JF, Heston MB, Warren MF et al (2024) Relationships between microbiome-derived short chain fatty acids and Alzheimers disease pathology biomarkers: a human cohort study