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Two reviewers (HS and HJS) separately performed the data extraction and cross-checked the data

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For Energy and Athletic Performance : Adenosylcobalamin is beneficial for athletes or those with chronic fatigue due to its direct impact on energy production

As a potent antioxidant, Pyrroloquinoline quinone (PQQ) may also reduce lipid peroxidation, though its direct impact on GPX4 regulation remains further elucidated ( 4.3.2 Superoxide dismutase (SOD) and catalase (CAT) SOD and CAT are essential enzymes in the antioxidant defense system