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Given the risk of complications from uncontrolled diabetes, such as the increased risk of wound infections from hyperglycemia, it would be in a patients best interest to continue these medications in the perioperative setting

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IV delivery bypasses this, which can produce higher circulating levels.

[DOI] [PubMed] [Google Scholar] 27.Kedar NP

Moreover, such a small molecule could serve as a tool compound to interrogate the function of the ADP-ribosyltransferase tankyrase, which is proposed to expel TRF1 from shelterin, thereby promoting telomere extension 18,19,20,21