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We next examined SLC25A39 expression in the human bronchial epithelial cell line BEAS-2B, multiple LUAD cell lines (H1975, H1650, A549, H1299), and a primary LUAD cell line (pLUAD1)

This is why the FDA labeling for Mounjaro and Zepbound advises using backup contraception for 4 weeks after you start these medications or increase the dose

It's important to distinguish mild nutritional ketosis (generally benign) from diabetic ketoacidosis (a medical emergency), which is rare with GLP-1 receptor agonists alone but can occur if insulin doses are reduced too quickly

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