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As discussed previously, fine-tuning TCR activation is critical for optimal activity of T cells, preventing anergy or exhaustion

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214 Alzheimers disease (AD) Alzheimers disease (AD) is characterized by senile plaques and neurofibrillary tangles (NFTs) caused by amyloid- and phosphorylated tau deposition

Upregulation of ATF4 and downregulation of translational initiation are hallmarks of the ISR, 55 we therefore analyzed the expression of ISR-related genes