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10.1021/jf5027247 101 VanduchovaA.TomankovaV.AnzenbacherP.AnzenbacherovaE

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The cystine/glutamate antiporter system (xCT), a disulfide-linked heterodimer composed of SLC7A11 and SLC3A2, serves as the pathway for cystine uptake into cells, where it is reduced to cysteine for the synthesis of intracellular GSH