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however, this represents early-phase evidence only, and the mechanistic effects observed in trials including increased energy expenditure and lipolysis via glucagon receptor agonism have not yet been fully characterised in long-term human studies

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Physiology and Pharmacology

10.1055/s-2008-1065354 127 RamaekersV

Peptide therapy should be viewed as part of a comprehensive wellness approach that includes exercise, nutrition, sleep, and healthy lifestyle habits