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Liraglutide paved the way for GLP-1 therapies in obesity treatment, but most patients and clinicians now prefer semaglutide or tirzepatide because of stronger results and easier dosing

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Women using oral contraceptives should use a non-oral method or add a backup method for 4 weeks after initiating tirzepatide and for 4 weeks after each dose increase due to potential reduced contraceptive effectiveness

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