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For short-term storage (under 4 weeks), room temperature may be acceptable in a controlled climate, but it is not recommended for high-purity research materials

As your body adjusts the the medication, you will slowing increase the amount over several weeks to months until you have slowly and safely worked up to a weekly maintenance dose

The incidence of hyperammonemia in pediatric patients 12 to 17 years of age in clinical trials of another condition was 26% in patients taking topiramate at 100 mg/day (1.1 times the maximum recommended dosage of QSYMIA) and 14% in patients taking topiramate at 50 mg/day (0.6 times the maximum recommended dosage of QSYMIA), compared to 9% in patients taking placebo

It has also recently been approved by the Food and Drug Administration (FDA) to lower the risk of major adverse cardiovascular events (including stroke, heart attack, or death) in adults who have cardiovascular disease and obesity or are overweight

I have lost 24 pounds in 8 weeks