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It is evident in whole-animal studies where the underlying cellular and molecular mechanisms are difficult to resolve, and it is often studied in isolated tissues where tolerance can be measured as a rightward shift in the dose-response curve that may also be associated with a reduction in the maximum response

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HORIUCHI, N., ANDO, S., & SUZUKI, A

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Priority should be given to public awareness campaigns for vitamin D deficiency, emphasizing the importance of sunlight exposure and dietary diversification