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This cortisol-neutral profile is important because elevated cortisol is associated with increased appetite (particularly for high-calorie foods), abdominal fat accumulation, and metabolic complications

Zhuang Y, Zhu Z, Chi PH, et al

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Spiking experiments involved addition of known amounts of pure NAD and glutathione compounds individually at different stages of the extraction (Supplementary Table 1), followed by quantification using colorimetric assays