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A single shot before an event will give you the antioxidant and hydration boost, but the brightening side is cumulative, so consistency is what delivers it

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117 In an uncontrolled trial that included 50 men with poor sperm parameters, 600 mg NAC daily for three months led to improved sperm numbers, motility, and morphology, as well as increased testosterone and LH and decreased FSH levels

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Approximately 0.1% of this is lost per day by secretions into the gut, as not all these secretions are reabsorbed