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Secreted primarily by intestinal L-cells in response to food intake, GLP-1 enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes satiety

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Pinching the skin fold and injecting at 90 degrees ensures proper depth

CPAP therapy can be cumbersome and uncomfortable, so recommendations for CPAP are generally reserved for patients who experience excessive daytime sleepiness, those with comorbid hypertension, and those for whom their sleep disruption affects their quality of life