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Similarly, in the presence of the GLP-1R antagonist Exendin(939) (Ex9, 100 nM), Ex4 failed to relax cardiac pericytes (capillary diameters remained reduced by 16.22.6% of the initial diameter at n = 22 pericytes in 5 hearts, p = 5.1 10 4 compared to Ex4 only, one-way ANOVA with dks test on final-minute values, Fig

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Chiou HC, Lin MW, Hsiao PJ, Chen CL, Chiao S, Lin TY et al

Notably, testing in animals also showed that it worked without some of the drugs side effects such as nausea, constipation and significant loss of muscle mass