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Some examples of autoimmune connective tissue diseases include: Polymyositis and dermatomyositis Rheumatoid arthritis (RA) Scleroderma Sjogren's syndrome Systemic lupus erythematosus (SLE or lupus) Vasculitis Mixed connective tissue disease (MCTD) Symptoms of connective tissue diseases can vary depending on the specific condition and the parts of the body affected

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Anal Chem 79:31553163

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In addition, GPX4 has been shown to govern lipoxygenases activities in the AA metabolism ( 4 , 12-HETE, and 15-HETE) in the presence of GPX4 activator compound 102 ( Supplementary Figure S3B )