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In the early stages, MMPs such as MMP-1, MMP-3, and MMP-13 are transiently upregulated to clear cellular debris and remodel damaged tissue (131)

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We observed a marked decrease of gastric epithelial cell proliferation rates, protection against parietal cell death and a 90% reduction of gastritis, accompanied by normalized expression levels for all (pro-inflammatory) cytokines, confirming the suppression of the host immune response elicited by Helicobacter infection