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278 It can be caused by diverse virus families ranging from DNA (i.e., HBV, EBV, HSV-1) to RNA viruses (i.e., HCV, RSV, DENV, Influenza, ZIKA, HIV)

FIGURE 2 AMP-activated protein kinase (AMPK), Sirtuin-1, and peroxisome proliferator-activated receptor- (PPAR) coactivator-1 (PGC-1) in particular, play important roles in mitochondrial biogenesis ( + -dependent deacetylases family member owning deacetylating activity ( + ) levels