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One honest caveat from the data: because the Phase 2 curve had not clearly plateaued by the end of the study, the full ceiling of the effect is genuinely not yet known that is one of the questions the Phase 3 TRIUMPH program is designed to answer

It's that we don't know yet

(In simpler terms, scientists could rearrange the amino acids within the peptide to make the molecule more effective at activating target receptors.) Eventually, new analogs were synthesized that had both in vitro and in vivo activity [5]

PubMed Pejcic AV, Petrovic NZ, Djordjic MD, Milosavljevic MN