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The isozyme class is subsequently identified with an upper-case letter (e.g., "A" for alpha), followed by an Arabic numeral representing the class subfamily (or subunit)

High blood pressure (hypertension) is usually regulated by angiotensin-converting enzyme (ACE) via the kinin-kallikrein system (KKS) and the renin-angiotensin-aldosterone system (RAAS)

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