Typical dosing for Trulicity starts at 0.75 mg once a week and then increases to 1.5 mg, 3 mg or 4.5 mg as recommended by a healthcare provider
Direct manufacturer negotiation, structured eligibility criteria, and controlled copays demonstrate that affordable access is technically feasible
ATP6AP2, a regulator of LRP6/-catenin protein trafficking, promotes Wnt/-catenin signaling and bone formation in a cell type dependent manner
Meanwhile, Mankind Pharma is setting up a dedicated obesity division and plans to launch Mankind Nutrition with a specialized field force
Alternatives include other GLP-1 receptor agonists (such as dulaglutide or liraglutide), SGLT2 inhibitors (such as dapagliflozin or empagliflozin), DPP-4 inhibitors, or insulin therapy