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Indeed, certain metabolic compounds positively modulate the gene expression and associated protective cellular pathways and may contribute to limit drug abuse-related alterations and toxicity

Refractive Index (RI) and ultraviolet spectroscopy (UV) monitoring in Solid Phase Peptide Synthesis (SPPS): Used during coupling and deprotection, RI detects deviations in reaction completeness or reagent flow, while UV confirms Fmoc removal via characteristic absorbance

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The resolved strain was transformed again with the pJV53H to subsequently generate double mutants