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The research rationale established by NNMT-knockdown studies in diet-induced-obese mice is that inhibiting NNMT preserves intracellular NAD+ and SAM levels, which in adipocyte (fat-cell) models has been shown to suppress de novo lipogenesis

Studies have shown that it is relatively safe with minor side effects, which may include temporary redness, itching or headache at the injection site

Later, they are given monthly

Primary Research Objectives: Mitochondrial Efficiency: Analyzing the impact of NNMT inhibition on NAD+ availability and cellular energy production

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