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by age 60, that drops to approximately 80 ng/mLa 60% decline that directly correlates with visible aging, reduced healing capacity, and tissue degradation

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Int J Mol Sci 22:4416 Op den Kamp YJM, de Ligt M, Dautzenberg B, Kornips E, Esterline R, Hesselink MKC, Hoeks J, Schrauwen-Hinderling VB, Havekes B, Oscarsson J, Phielix E, Schrauwen P (2021) Effects of the SGLT2 inhibitor dapagliflozin on energy metabolism in patients with type 2 diabetes: a randomized, double-blind crossover trial