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The additive growth and functional demands that initiated the response to hepatic enzyme induction cover a wide range of stimuli including pregnancy and lactation, hormonal fluctuations, dietary constituents, infections associated with acute-phase proteins, as well as responses to exposure to xenobiotics

While the branded product was voluntarily discontinued by the manufacturer for commercial reasons (not safety concerns), sermorelin continues to be prescribed off-label through 503A and 503B compounding pharmacies

doi: 10.3389/fped.2018.00412 5 JasonLAKatzBZSunnquistMTorresCCotlerJBhatiaS

Immediate medical attention is necessary in these situations to prevent organ damage and other complications

Clinical studies show it is well-tolerated when taken responsibly