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It does not reach inside your skeletal muscle cells to tell mitochondria what to burn

This highly coordinated network is dependent on: 1) the coordination and division of labor among multiple organs and cell types, such as the involvement of the liver in lipid synthesis, -oxidation, the conversion of cholesterol to bile acids, the role of adipose tissue in triglyceride (TG) storage and the thermogenesis of brown adipocytes [8]

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The increasing prevalence of HTN is linked to factors like sedentary lifestyles, smoking and alcohol consumption, employment in manufacturing industries, increased stress, unhealthy diets, and rising life expectancy (12)

But the magic doesnt stop there