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Injectable vitamin B12, which can treat significant deficiencies, may cause the following common side effects: More serious side effects of vitamin B12 injections can include: irregular heartbeat heart palpitations hives or a skin rash Vitamin B12 can cause very rare but serious allergic reactions, or anaphylaxis

Multiple controlled trials in people have looked at NAD+ supplementation, including studies that measured actual intracellular levels before and after

Endocrinology 155 , 2126 (2014)

Doing so may not improve effectiveness and could increase the likelihood of side effects

Those that prescribe vitamins as a primary treatment modality, such as naturopaths, will love this study and feed on it