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Wegovy is given through a pen injection, under the skin weekly, and begins with a25 mg dose, per week for the initial four weeks before gradually increasing every four weeks until it reaches a goal of 2.4 mg per week as the maximum dosage

Makes weight loss attainable

This early phase reflects the medication's mechanism: it slows gastric emptying (the rate your stomach releases food) and triggers satiety signals in your hypothalamus

These findings are broadly compatible with the possibility that GLP-1 signalling may attenuate cue-driven incentive salience, but they do not yet establish a single dopaminergic mechanism as the definitive explanation for the observed behavioural changes

12 Peptide pharmacology reviewBackground on short peptide bioregulators and their proposed neuroendocrine mechanisms