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This study shows that protofibrillar -synuclein can permeabilize vesicles, allowing the leakage of small molecules, such as dopamine, which could potentially lead to an increase in cytoplasmic dopamine levels

The research goal is potent, selective NNMT inhibitors with favourable selectivity profiles

(Maywood) 233 , 779791 (2008)

Among these, soybean ( Glycine max ) represents a particularly promising system for translational application

The pathophysiology of SAH is multifactorial, involving direct hepatotoxicity from alcohol metabolites, oxidative stress, dysregulated immune activation, gut dysbiosis with increased intestinal permeability, impaired hepatic regeneration, and genetic susceptibility