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If an exact donor match cannot be found, an alternative to this procedure is the use of blood from the umbilical cord of an unrelated donor

For example, ongoing research has explored the use of single-cell transcriptomics to establish immune system baselines in ME/CFS patients to compare ME/CFS patients and to detect deviations following cardiopulmonary exercise testing (Vu et al., 2024)

doi:10.1056/NEJMoa2206038

Kraguljac NV, Reid M, White D, Jones R, den Hollander J, Lowman D, et al

Furthermore, ACTL6A KD via shRNA inhibited patient-derived organoid (PDO) growth, and organoids with ACTL6A KD had a compact morphology with no lumen (Fig