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p53 activation enhanced DNA repair, genome integrity, and suppressed CCF formation

Simultaneously, studies using molecular biology detection and pharmacological intervention confirmed that heat stress triggers cPLA2 activation and increases the level of its metabolite arachidonic acid to participate in lipid peroxidation in the mouse heatstroke model, further promoting the occurrence of ferroptosis, thereby aggravating the progression of ALI after heat stress [48]

Glutathione plays a vital role in supporting immune cell function