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Nrf2 plays a critical role in mitigating lipid peroxidation and ferroptosis

We note that our UbiCRest analysis could not technically distinguish TRIP12 addition of branched K29-linkages onto the most proximal ubiquitin moiety of the previously assembled K48-linked chains

Marked reductions in antioxidant enzymes (SOD, catalase, GST) and reduced glutathione (GSH), alongside elevated TBARS levels, indicate significant oxidative imbalance [4]

The growth and GPX activity were measured

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