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10.1039/C3MT00185G 263

TABLE 6 Pharmacokinetic parameters of BPC157 in dogs following repeated intramuscular administration at a dose of 30 g/kg for seven consecutive days (mean SD, n = 6)

The source data of this paper are collected in the following database record: biostudies:S-SCDT-10_1038-S44321-024-00090-6

Clinical trial data for FDA-approved GLP-1 receptor agonists demonstrates: Significant weight reduction: Meaningful mean body weight reduction in trial participants (see FDA-approved labeling for specific approved products) Cardiorenal protection: Reduced risk of major adverse cardiovascular events and kidney disease progression Improved lipid profiles: Decreased triglycerides and increased HDL cholesterol Blood pressure reduction: Modest but clinically significant decreases in systolic blood pressure Reduced inflammation: Decreased inflammatory markers associated with metabolic syndrome Note: Clinical outcomes cited above reflect published trial data for FDA-approved GLP-1 receptor agonists

Insulin , glucocorticoids and the control of inflammatory responses