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The results showed that in GCL of diabetic rats, the expression of LC3A/B was enhanced and p62 was reduced compared with the control group, whereas these results were reversed in liraglutide treatment rats (Figures 7AD)

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Inspired by nature, Gradinaru lab has over the past decade used the process of directed evolutiona technique pioneered at Caltech by Nobel Laureate Frances Arnoldto guide the evolution of vectors and enhance their ability to cross the BBB