Active Ingredients Per Serving (2 Capsules)
Ethics declarations Disclosure Avery Brown, Helena Sergent, Alexander Hien Vu, Helen Liu, Jason Fisher, Eduardo Somoza, Tony Mei, Jeffrey Lipman, Julia Park, Patricia Chui, John Saunders, Marina Kurian, Loic Tchokouani, George Ferzli, Christine Ren-Fielding, Manish Parikh, Megan Jenkins have no conflicts of interest or financial ties to disclose
Baseline estimated renal function was normal (eGFR 90 mL/min/1.73m2) in 65.9%, mildly impaired (eGFR 60 to 90 mL/min/1.73m2) in 28.5% and moderately impaired (eGFR 30 to 60 mL/min/1.73m2) in 5.4% of the patients
This dose was chosen after the previous clinical study showed that the lower dose of 200 mg had an effect comparable to the higher doses of 400 and 800 mg for the main biochemical and molecular parameters studied, and better efficacy on hypoglycemic action
Both are available as weekly subcutaneous injections, and both are widely used as compounded formulations