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The mitochondrial DOX-Fe 2+ complex induces triggers lipid peroxidation, resulting in mitochondria-dependent ferroptosis and decreased cardiac function in mice, which is reflected in significantly reduced left ventricular ejection fraction and myocardial fibrosis

These can also be administered rectally, although the practice is uncommon and not advised

The generation of 1 O 2 implies the collision of two peroxyl radicals (ROO ) with formation of excited species, 1 O 2 itself and excited carbonyls, followed by photoemission

10.1074/jbc.271.26.15420 J

These are known as vitamin K3 (menadione), vitamin K4 (menadiol diacetate), and vitamin K5