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Acknowledgements We gratefully acknowledge the valuable cooperation of Huiping Ma (Center of Animal Experiment, Chinese Peoples Liberation Army Joint Logistic Support Force 940th Hospital) in preparing this animal model experiment

& Li, R

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Circulating INSL-5 levels are estimated to be in the picomolar range (164, 172), which is several orders of magnitude lower than the EC 50 of INSL-5 on RXRP4 (166) and the supraphysiological concentrations used in the majority of insulin secretion experiments may have contributed to the conflicting results

J Immunol (1988) 140:1895902