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Holth JK et al (2020) The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

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For instance, To establish a meaningful human advantage, clinical trials would need carefully controlled measurements such as dual-energy X-ray absorptiometry, magnetic resonance imaging, strength testing, physical-function outcomes, dietary assessment, and comparisons adjusted for total weight loss

The researchers collected participant blood samples and performed carotenoid extraction on fasting serum samples

For detailed protocols, see our Reconstitution Guide