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In previous studies, the expansion of polyglutamine (polyQ) bundles to 36 or more glutamine repeats will cause the HTT protein to misfold and aggregate, leading to neuronal death and symptoms of Huntingtons disease (Mangiarini et al., 1996)

The cost and federal policy change, along with the looming possibilities of an economic downturn and cuts in federal funding for state programs, likely led state leaders to make hard decisions about what they should cover, said Brad Wright, chair of health services policy and management at the University of South Carolinas Arnold School of Public Health