Tufted astrocytes, characterised by accumulation of tau in proximal astrocytic processes, represent the histopathological hallmark of progressive supranuclear palsy, a rare neurodegenerative disorder with progressive impairment of balance, walking, eye movement, muscular rigidity, dysarthria, and dysphagia
Proc Natl Acad Sci USA 99: 35053510 Gross E, Kastner DB, Kaiser CA, Fass D (2004) Structure of Ero1p, source of disulfide bonds for oxidative protein folding in the cell
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