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Hyaluronic acid and corticosteroids: These compounds have anti-inflammatory effects, reducing pain in the joint

Animal studies have reported observations of altered body composition and reduced adiposity in NNMT-inhibited models

Patients with high LOX-expressing tumors have poor overall survival

And I think with obesity, it might work the same way once we have greater numbers of choices in the clinic

In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression